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Heparin, methotrexate, cyclosporine, warfarin, and phenytoin may all raise calcium losses, and 10 mg day of corticosteroids can generate osteopenia and hypercalciuria.

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Information about Methotrexate.

12 mg/m2 intrathecally every 2 to 5 days until the average cost of methotrexate count of the CSF returns to normal. At this point.one additional dose is advisable. Administration at intervals of less than 1 week may result in increased subacute toxicity.

Do not receive a “live” vaccine while using methotrexate.or you could develop a serious infection. Live vaccines include measles.mumps.rubella (MMR).polio.rotavirus.typhoid.yellow fever.varicella (chickenpox).and zoster (shingles).

Methotrexate is usually given after other medications have been tried without successful treatment of symptoms.

Examples of drugs that can cause interactions with methotrexate average cost of methotrexate listed below.

Before using this medication.tell your doctor or pharmacist your medical history.especially of. liver disease.kidney disease.lung disease (such as pulmonary fibrosis).alcohol use.suppressed immune system.blood cell/bone marrow disorders.stomach/intestinal diseases (such as peptic ulcer.ulcerative colitis).any active infection (including chickenpox or recent exposure to it).folic acid deficiency.

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if you have ra you should take methotrexate in combination with one of the other drugs, it works much better.