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Patients should inform physicians and dentists that they are taking clopidogrel before any surgery is scheduled and before any new medicinal product is taken.

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Lopid mainly undergoes oxidation of a ring methyl cheap lopid and to successively form a hydroxymethyl and a carboxyl metabolite. Approximately seventy percent of the administered human dose is excreted in the urine.mostly as the glucuronide conjugate.with less than 2% excreted as unchanged gemfibrozil. Six percent of the dose is accounted for in the feces. Gemfibrozil is highly bound to plasma proteins and there is potential for displacement interactions with other drugs (see PRECAUTIONS ).

This medicine is not right for everyone. Do not use it if you had an allergic reaction to gemfibrozil.

LOPID is a lipid regulating agent which decreases serum triglycerides and very low density lipoprotein (VLDL) cholesterol.and increases high density lipoprotein (HDL) cholesterol. While modest decreases in total and low density lipoprotein (LDL) cholesterol may be observed with LOPID therapy.treatment of patients with elevated triglycerides cheap lopid and to Type IV hyperlipoproteinemia often results in a rise in LDL-cholesterol. LDL-cholesterol levels in Type IIb patients with elevations of both serum LDL-cholesterol and triglycerides are.in general.minimally affected by LOPID treatment. however.LOPID usually raises HDL-cholesterol significantly in this group. LOPID increases levels of high density lipoprotein (HDL) subfractions HDL2 and HDL3.as well as apolipoproteins AI and AII. Epidemiological studies have shown that both low HDL-cholesterol and high LDL-cholesterol are independent risk factors for coronary heart disease.

Take the missed dose as soon as you remember it. However.if it is almost time for the next dose.skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

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