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Compazine is not approved for use in psychotic conditions related to dementia. This medicine may increase the risk of death in older adults with dementia-related conditions.
There is evidence that phenothiazines are excreted in the breast milk of nursing mothers. Caution should be exercised when prochlorperazine is administered to a nursing woman.
Antipsychotic drugs elevate prolactin levels. the elevation persists during chronic administration. Tissue culture experiments indicate that approximately 1/3 of human breast cancers are prolactin-dependent in vitro .a factor of potential importance if the prescribing of these drugs is contemplated in a patient with a previously detected breast cancer. Although disturbances such as galactorrhea.amenorrhea.gynecomastia and impotence have been reported.the clinical significance of elevated serum prolactin levels is unknown for most patients. An increase in mammary neoplasms has been found in rodents after chronic administration of antipsychotic drugs. Neither clinical nor epidemiologic studies conducted to date.however.have shown an association between chronic administration of these drugs and mammary tumorigenesis. the available evidence is considered too limited to be conclusive at this time.
Prochlorperazine comes as a tablet to take by mouth and as a suppository to place in the rectum. Prochlorperazine tablets are usually order compazine for three to four times a day by adults and are usually given to children one to three times a day. Prochlorperazine suppositories are usually inserted twice a day. Use prochlorperazine at around the same time(s) every day. Follow the directions on your prescription label carefully.and ask your doctor or order compazine for to explain any part you do not understand. Use prochlorperazine exactly as directed. Do not use more or less of it order compazine for use it more often than prescribed by your doctor.
Extrapyramidal reactions include acute dystonia.akathisia.parkinsonism.and tardive dyskinesia. These reactions have lasted months to years.especially in elderly patients with brain damage.
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