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Tell your doctor if you are breastfeeding.or if you have kidney disease.liver disease.asthma.high blood pressure.heart or blood vessel problems.heart failure.a recent heart attack.or a history of stomach ulcers or bleeding problems. Tell your doctor if you smoke or drink alcohol.

heart disease.high blood pressure.high cholesterol.diabetes.or if you smoke. a history of heart attack.stroke.or blood clot. a history of stomach ulcers or bleeding. asthma. fluid retention. or liver disease.

When NSAIDs were administered with aspirin.the protein binding of NSAIDs were reduced.although the clearance of free NSAID was not altered. The clinical significance of this interaction is not known. See Table 2 for clinically significant drug interactions of NSAIDs with aspirin ( see PRECAUTIONS. Drug Interactions ) .

kidney problems–little ponstel cost no urinating.painful or difficult urination.swelling in your feet or ankles.feeling tired or short of breath.

the first sign of any skin rash.no matter how mild. shortness of breath (even with mild exertion). swelling or rapid weight gain. signs of stomach bleeding –bloody or tarry stools.coughing up blood or vomit that looks like coffee grounds. liver problems –nausea.upper stomach pain.itching.tired feeling.flu-like symptoms.loss of appetite.dark urine.clay-colored stools.jaundice (yellowing of the skin or eyes). kidney problems –little or no urinating.painful or difficult urination.swelling in your feet or ankles.feeling tired or short of breath. low red blood cells (anemia) –pale skin.feeling light-headed or short of breath.rapid heart rate.trouble concentrating. or severe skin reaction –fever.sore throat.swelling in your face or tongue.burning in your eyes.skin pain followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling.

It is used to ease pain. It is used to ease painful period (menstrual) cycles. It may be given to you for other reasons. Talk with the doctor.

This is not a list of all drugs or health problems that interact with Ponstel (mefenamic acid).

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