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Adverse Reactions and Abnormal Laboratory Tests . Renal dysfunction.toxic nephropathy.hepatic dysfunction including cholestasis.aplastic anemia.hemolytic anemia.serum sickness-like reaction.hemorrhage.agranulocytosis.and pancytopenia.
Protein binding of cefpodoxime ranges from 22 to 33% in serum and from 21 to 29% in plasma.
This medication may rarely cause a severe intestinal condition (Clostridium difficile-associated diarrhea) due to a type of resistant bacteria. This condition may occur during treatment or weeks to months order vantines treatment order vantines stopped. Tell your doctor right away if you develop. persistent diarrhea.abdominal or stomach pain/cramping.blood/mucus in your stool. Do not use anti-diarrhea or opioid medications if you have any of these symptoms because these products may make them worse.
Elimination of cefpodoxime is reduced in patients with moderate to severe renal impairment ( Table 1. Susceptibility Test Interpretive Criteria for Cefpodoxime 2.
Appropriate specimens for bacteriological examination should be obtained in order to isolate and identify causative organisms and to determine their susceptibility to cefpodoxime. Therapy may be instituted while awaiting the results of these studies. Once these results become available.antimicrobial therapy should be adjusted accordingly.
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