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5 and 5 times the mrhd for metoprolol and hydrochlorothiazide, respectively produced no teratogenic effects.

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Information about Toprol.

Consider initiating TOPROL-XL therapy at doses lower than those recommended for a given indication. gradually increase dosage to optimize therapy.while monitoring closely for adverse events.

Heart attack happens when a blood clot completely obstructs a coronary artery supplying blood to the heart muscle. A heart attack.

congestive heart failure. low blood pressure. pheochromocytoma. problems with circulation (such as Raynaud’s syndrome). asthma.bronchitis.emphysema. diabetes. depression. liver or kidney disease. a thyroid disorder. or severe allergies.

Toprol falls into category C. In animal studies.pregnant animals were given this medication and had some babies born with problems. No well-controlled studies have been done in humans.though. Therefore.this medication may be used if the potential benefits to the mother outweigh the potential risks to the unborn child.

This is not a complete list of Toprol side effects. Ask your doctor or pharmacist for more information.

Missed dose. Take a dose as soon as you remember. If it is almost time for your next dose.wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.

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pain in the muscles, tendons, ligaments, nerves, and bones have been reported with metoprolol.